Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29624542 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| Water SCHEMBL6221139 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| Hydrochloric Acid SCHEMBL21857700 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| Hydrochloric Acid SCHEMBL29700837 | 0.98 | KDM4E (0.55) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL8989496 | 0.81 | TMPRSS4 (0.47) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL24991566 | 0.79 | MEN1 (0.45) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL4099416 | 0.79 | GAA (0.41) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL479494 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL30401857 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL6638863 | 0.78 | DPP4 (0.53) | KDM4EALDH1A1MEN1KMT2ATMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117907497-A | Analysis method for quickly searching biomarker based on three-dimensional combination derivatization | 厦门大学 | 2024-04-19 | — | — | CN | claimed |
| CN-116969925-B | Heteroaryl-triazole compounds | BAYER AG (DE) | 2026-05-26 | — | — | CN | disclosed |
| US-12610949-B2 | Heteroaryl-triazole compounds as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-04-28 | — | — | US | disclosed |
| EP-4041393-B1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AG (DE) | 2026-04-08 | — | — | EP | disclosed |
| EP-4711365-A1 | THIAZOLE DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2026-03-18 | — | — | EP | disclosed |
| EP-4043463-B1 | FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2025-11-26 | — | — | EP | disclosed |
| EP-4643644-A2 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| US-12454533-B2 | Fused ring derivative having MGAT-2 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2025-10-28 | — | — | US | disclosed |
| EP-4051673-B1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-24 | — | — | EP | disclosed |
| CN-114630825-B | Condensed with pesticidal activity bicyclic heteroaromatic compounds | 先正达农作物保护股份公司 | 2025-05-16 | — | — | CN | disclosed |
| US-7279469-B2 | Diaminotriazoles useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-10-09 | — | — | US | disclosed |
| US-20050261331-A1 | Substituted pyrrolopyridines | ASTRAZENECA AB (SE) | 2005-11-24 | — | — | US | disclosed |
| EP-1562589-A2 | DIAMINOTRIAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES | Vertex Pharmaceuticals Incorporated (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1539757-A1 | SUBSTITUTED PYRROLOPYRIDINES | AstraZeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| US-20040214817-A1 | Diaminotriazoles useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2004-10-28 | — | — | US | disclosed |
| WO-2004046120-A2 | DIAMINOTRIAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2004-06-03 | — | — | WO | disclosed |
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2004-04-01 | — | — | US | disclosed |
| WO-2004016609-A1 | SUBSTITUTED PYRROLOPYRIDINES | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | WO | disclosed |
| EP-1333031-A1 | BICYCLIC TRIAZOLONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-5569763-A | USEFUL AS ORGANIC NONLINEAR OPTICAL MATERIAL AND A HIGHLY SENSITIVE COLORING CHELATION AGENT | KABUSHIKI KAISHA TOSHIBA (JP) | 1996-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12610949-B2 | Heteroaryl-triazole compounds as pesticides | CTRL, PTMS, DDT | KDM4E 2954/4885ALDH1A1 3469/4885L3MBTL1 156/4885 |
| US-20050261331-A1 | Substituted pyrrolopyridines | ITK, WEE1, PDPK1 | KDM4E 1691/4885ALDH1A1 1591/4885L3MBTL1 4156/4885 |
| US-12454533-B2 | Fused ring derivative having MGAT-2 inhibitory activity | MGAT1, MGAT2, MGAT3 | KDM4E 1480/4885ALDH1A1 1610/4885L3MBTL1 5/4885 |
| US-20040214817-A1 | Diaminotriazoles useful as inhibitors of protein kinases | MAP3K20, MAP3K1, MAP3K5 | KDM4E 1531/4885ALDH1A1 3235/4885L3MBTL1 3992/4885 |
| US-20040063580-A1 | Bicyclic triazolone derivatives and a herbicides containing the same | WEE1, WEE2, BAK1 | KDM4E 1331/4885ALDH1A1 318/4885L3MBTL1 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.