Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.35 |
| ▸ | ATF1 | P18846 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28667854 | 1.00 | SYK (0.44) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL30236562 | 1.00 | SYK (0.44) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL28667855 | 1.00 | SYK (0.44) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL24786905 | 0.88 | SYK (0.42) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL23618810 | 0.88 | POLB (0.39) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL23618785 | 0.84 | GSK3A (0.44) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL31612079 | 0.82 | SYK (0.49) | SYKMAPTMEN1KMT2AKDM4E | |
| SCHEMBL23618710 | 0.81 | SYK (0.44) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL30235825 | 0.81 | SYK (0.44) | SYKPOLBMAPTMEN1KMT2A | |
| SCHEMBL24786349 | 0.77 | SYK (0.44) | SYKMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377676-A | Crystalline forms of purine derivatives and pharmaceutical compositions thereof | 成都百裕制药股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-113121574-B | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| WO-2023274310-A1 | CRYSTAL FORM OF PURINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | 成都百裕制药股份有限公司 | 2023-01-05 | — | — | WO | disclosed |
| US-20220402920-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2022-12-22 | — | — | US | disclosed |
| CN-113121574-A | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2021-07-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402920-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | DPYD, PNP, TYMP | SYK 1822/4885POLB 85/4885MAPT 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.