⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19137053 | 0.76 | CXCR1 (0.36) | — | |
| SCHEMBL103443 | 0.76 | — | — | |
| SCHEMBL8644281 | 0.76 | CXCR1 (0.41) | — | |
| SCHEMBL26855501 | 0.74 | — | — | |
| SCHEMBL8260376 | 0.73 | — | — | |
| SCHEMBL8260827 | 0.73 | — | — | |
| SCHEMBL6850696 | 0.73 | — | — | |
| SCHEMBL11774918 | 0.72 | — | — | |
| SCHEMBL29363407 | 0.72 | — | — | |
| SCHEMBL8702899 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402907-A1 | MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE | YALE UNIVERSITY | 2022-12-22 | — | — | US | disclosed |