Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698543 | 0.86 | MAPK14 (0.48) | KDM1AFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL28420518 | 0.83 | MAPK14 (0.48) | FFAR1MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL15968872 | 0.80 | KDM1A (0.48) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31166800 | 0.80 | KDM1A (0.44) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL31114134 | 0.76 | MAOB (0.55) | FFAR1MRGPRX4 | |
| SCHEMBL31114193 | 0.76 | MAPT (0.48) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL10266023 | 0.76 | KDM1A (0.50) | KDM1AMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL23887259 | 0.75 | MAPK14 (0.44) | KDM1AFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL30176334 | 0.75 | MAPK14 (0.44) | KDM1AFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL15129422 | 0.75 | KDM1A (0.60) | KDM1AFFAR1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | disclosed |