Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 17/20 | 0.72 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765708 | 0.94 | IKZF2 (0.75) | IKZF2IKZF1 | |
| SCHEMBL30369064 | 0.94 | IKZF2 (0.75) | IKZF2IKZF1 | |
| SCHEMBL30619768 | 0.91 | IKZF2 (0.70) | IKZF2IKZF1 | |
| SCHEMBL20774914 | 0.91 | IKZF2 (0.70) | IKZF2IKZF1 | |
| SCHEMBL30368787 | 0.91 | IKZF2 (0.70) | IKZF2IKZF1 | |
| SCHEMBL20765248 | 0.90 | IKZF2 (0.73) | IKZF2IKZF1 | |
| SCHEMBL30368716 | 0.90 | IKZF2 (0.73) | IKZF2IKZF1 | |
| SCHEMBL30619758 | 0.90 | IKZF2 (0.69) | IKZF2IKZF1 | |
| SCHEMBL20765278 | 0.89 | IKZF2 (0.76) | IKZF2IKZF1 | |
| SCHEMBL30369147 | 0.89 | IKZF2 (0.76) | IKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672949-B1 | 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-12-21 | — | — | EP | disclosed |