Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MARS1 | P56192 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IARS1 | P41252 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16708473 | 0.85 | TMPRSS2 (0.49) | TMPRSS2TDP1ADORA1 | |
| SCHEMBL16708472 | 0.84 | TMPRSS2 (0.42) | TMPRSS2P2RY6P2RY14NT5EALDH1A1 | |
| SCHEMBL24789732 | 0.80 | TMPRSS2 (0.45) | TMPRSS2ALDH1A1TSHRMGLLTDP1 | |
| SCHEMBL24917272 | 0.80 | TMPRSS2 (0.43) | TMPRSS2ALDH1A1TSHRMGLLTDP1 | |
| SCHEMBL24917594 | 0.79 | TMPRSS2 (0.61) | TMPRSS2ALDH1A1TSHRMGLLTDP1 | |
| SCHEMBL25917189 | 0.78 | TMPRSS2 (0.35) | TMPRSS2P2RY6P2RY14NT5EALDH1A1 | |
| SCHEMBL25912544 | 0.77 | TMPRSS2 (0.43) | TMPRSS2TDP1ADORA1POLB | |
| SCHEMBL16708477 | 0.77 | TMPRSS2 (0.47) | TMPRSS2TDP1ADORA1POLB | |
| SCHEMBL19101893 | 0.76 | BCHE (0.40) | TMPRSS2NT5E | |
| SCHEMBL16708509 | 0.76 | TMPRSS2 (0.41) | TMPRSS2P2RY6P2RY14NT5EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022265964-A1 | ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS | VenatoRx Pharmaceuticals, Inc. (US) | 2022-12-22 | — | — | WO | disclosed |