Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479969 | 1.00 | TACR3 (1.00) | TACR3 | |
| SCHEMBL2475756 | 0.94 | TACR3 (0.98) | TACR3 | |
| SCHEMBL2479991 | 0.94 | TACR3 (0.98) | TACR3 | |
| SCHEMBL2475833 | 0.94 | TACR3 (1.00) | TACR3 | |
| SCHEMBL2477306 | 0.94 | TACR3 (1.00) | TACR3 | |
| SCHEMBL2477130 | 0.93 | TACR3 (1.00) | TACR3 | |
| SCHEMBL2481748 | 0.93 | TACR3 (1.00) | TACR3 | |
| SCHEMBL2478117 | 0.91 | TACR3 (1.00) | TACR3 | |
| SCHEMBL2477307 | 0.91 | TACR3 (1.00) | TACR3 | |
| SCHEMBL2477089 | 0.91 | TACR3 (1.00) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | claimed |
| EP-1656349-B1 | CYCLOPROPYL DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2011-10-12 | — | — | EP | disclosed |