SCHEMBL24796661

SCHEMBL24796661

CC1(C)[C@@H]2C(=O)N(CCNC(=O)CSCC(=O)NC3CCCC3)C(=O)[C@@H]21

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 4/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ LMNA P02545 1/20 0.43
▸ ATM Q13315 1/20 0.41
▸ RXFP1 Q9HBX9 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ POLB P06746 3/20 0.39
▸ ALDH1A1 P00352 3/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796662 0.98 HPGD (0.40) HPGDKMT2ASMN1; SMN2LMNAATM
SCHEMBL21389261 0.85 ATM (0.50) HPGDKMT2ASMN1; SMN2LMNAATM
SCHEMBL21389270 0.85 HPGD (0.44) HPGDKMT2ASMN1; SMN2LMNAATM
SCHEMBL24796295 0.84 ATM (0.49) HPGDKMT2ASMN1; SMN2LMNAATM
SCHEMBL21389337 0.84 CYP1A2 (0.38) KMT2ASMN1; SMN2L3MBTL1POLBALDH1A1
SCHEMBL24796307 0.83 HPGD (0.42) HPGDKMT2ASMN1; SMN2LMNARXFP1
SCHEMBL21389177 0.83 GAA (0.36) SMN1; SMN2LMNAL3MBTL1GAAPOLB
SCHEMBL24796401 0.82 HPGD (0.41) HPGDKMT2ASMN1; SMN2LMNAATM
SCHEMBL24796649 0.82 ATM (0.46) HPGDKMT2ASMN1; SMN2LMNAATM
SCHEMBL21389327 0.82 HPGD (0.41) HPGDKMT2ASMN1; SMN2LMNARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR HPGD 2144/4885KMT2A 2741/4885SMN1; SMN2 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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