Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 5/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20789202 | 0.90 | KDM4E (0.39) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL25518990 | 0.90 | KDM4E (0.38) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL24797699 | 0.90 | KDM4E (0.38) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL25524625 | 0.90 | KDM4E (0.38) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL24797703 | 0.90 | KDM4E (0.38) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL25519259 | 0.90 | KDM4E (0.38) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL25524545 | 0.90 | KDM4E (0.38) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL25531146 | 0.90 | KDM4E (0.38) | KDM4ERAF1BRAFMMP12MMP13 | |
| SCHEMBL24797704 | 0.86 | KDM4E (0.36) | KDM4ERAF1BRAFRORCMAPK14 | |
| SCHEMBL20789152 | 0.86 | ACKR3 (0.37) | KDM4ERAF1BRAFMMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108663-A1 | SUBSTITUTED ARYL COMPOUND | Simcere Pharmaceutical Co., Ltd. (CN) | 2022-12-28 | — | — | EP | disclosed |