Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587428 | 0.89 | MC4R (0.40) | MC4RIDO1HRH3KDM4EALDH1A1 | |
| SCHEMBL13635723 | 0.86 | MC4R (0.36) | MC4RIDO1NCF1 | |
| SCHEMBL11577367 | 0.84 | MC4R (0.37) | MC4RIDO1NCF1 | |
| SCHEMBL25921483 | 0.82 | MC4R (0.41) | MC4RIDO1HRH3KDM4EALDH1A1 | |
| SCHEMBL24507522 | 0.82 | MC4R (0.41) | MC4RIDO1HRH3KDM4EALDH1A1 | |
| SCHEMBL26178209 | 0.81 | MC4R (0.38) | MC4RIDO1HRH3KDM4EALDH1A1 | |
| SCHEMBL3588742 | 0.81 | MC4R (0.38) | MC4RIDO1HRH3KDM4EALDH1A1 | |
| SCHEMBL24418758 | 0.78 | IDO1 (0.50) | MC4RIDO1HRH3KDM4EALDH1A1 | |
| SCHEMBL23987733 | 0.76 | HRH3 (0.35) | MC4RIDO1HRH3KDM4EALDH1A1 | |
| SCHEMBL3597765 | 0.74 | MC4R (0.35) | MC4RIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466943-B1 | DIPHENYLAMINOPYRIMIDINE AND TRIAZINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | ARROMAX PHARMATECH CO LTD (CN) | 2022-12-28 | — | — | EP | disclosed |