⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986949 | 0.95 | — | — | |
| SCHEMBL3411831 | 0.86 | NPC1 (0.37) | — | |
| SCHEMBL2415833 | 0.78 | — | — | |
| SCHEMBL3415811 | 0.76 | — | — | |
| SCHEMBL3412356 | 0.76 | — | — | |
| SCHEMBL598956 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL2466724 | 0.75 | PPARD (0.35) | — | |
| SCHEMBL1733641 | 0.75 | CYP1A2 (0.31) | — | |
| SCHEMBL4823005 | 0.74 | — | — | |
| SCHEMBL4337322 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8444955-B2 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-8216548-B2 | Radiofluorination methods | GE HEALTHCARE AS (NO) | 2012-07-10 | — | — | US | disclosed |
| EP-2376432-A1 | NOVEL EICOSANOID DERIVATIVES | Max-Delbrück-Centrum für Molekulare Medizin (MDC) (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20100196270-A1 | RADIOFLUORINATION METHODS | GE HEALTHCARE AS (NO) | 2010-08-05 | — | — | US | disclosed |
| WO-2010081683-A1 | NOVEL EICOSANOID DERIVATIVES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2010-07-22 | — | — | WO | disclosed |
| EP-2195037-A2 | RADIOFLUORINATION METHODS | GE Healthcare UK Limited (GB) | 2010-06-16 | — | — | EP | disclosed |
| US-20100034740-A1 | RADIOFLUORINATION METHODS | GE HEALTHCARE AS (NO) | 2010-02-11 | — | — | US | disclosed |
| EP-2114464-A2 | RADIOFLUORINATION METHODS | GE Healthcare AS (NO) | 2009-11-11 | — | — | EP | disclosed |
| WO-2009035959-A2 | RADIOFLUORINATION METHODS | GE HEALTHCARE LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |
| WO-2008083191-A2 | RADIOFLUORINATION METHODS | GE HEALTHCARE AS (NO) | 2008-07-10 | — | — | WO | disclosed |