SCHEMBL24799622

SCHEMBL24799622

CNc1ccnc(C(=O)NC2(C#N)CCC2)c1

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ANO1 Q5XXA6 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21218974 0.89 ANO1 (0.62) ANO1
SCHEMBL24799373 0.82 ANO1 (0.57) ANO1
SCHEMBL31306648 0.76 ANO1 (0.53) ANO1
SCHEMBL21198011 0.76 ANO1 (0.53) ANO1
SCHEMBL31306119 0.76 ANO1 (1.00) ANO1
SCHEMBL21198167 0.76 ANO1 (1.00) ANO1
SCHEMBL21198741 0.75 ANO1 (1.00) ANO1
SCHEMBL31306122 0.75 ANO1 (1.00) ANO1
SCHEMBL21218939 0.75 ANO1 (0.68) ANO1
SCHEMBL30044683 0.75 ANO1 (0.54) ANO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743406-B1 TMEM16A MODULATORS TMEM16A LTD (GB) 2022-12-28 EP disclosed