Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.79 |
| ▸ | JAK1 | P23458 | 20/20 | 0.79 |
| ▸ | TYK2 | P29597 | 20/20 | 0.79 |
| ▸ | JAK3 | P52333 | 12/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21757002 | 0.90 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757020 | 0.90 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757106 | 0.90 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL23584394 | 0.90 | JAK2 (0.90) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757090 | 0.88 | JAK2 (1.00) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL24742739 | 0.88 | JAK2 (0.81) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757000 | 0.88 | JAK2 (1.00) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL21757111 | 0.88 | JAK2 (1.00) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL24742801 | 0.87 | JAK2 (0.73) | JAK2JAK1TYK2JAK3CYP2C19 | |
| SCHEMBL23424195 | 0.84 | JAK2 (1.00) | JAK2JAK1TYK2JAK3CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108664-A1 | CRYSTALLINE FORM OF JAK INHIBITOR AND APPLICATION THEREOF | Zhuhai United Laboratories Co., Ltd (CN) | 2022-12-28 | — | — | EP | disclosed |