Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29348737 | 0.81 | CRBN (0.47) | CRBNDDB1 | |
| SCHEMBL24206784 | 0.80 | CRBN (0.49) | CRBNDDB1 | |
| SCHEMBL24204353 | 0.80 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL25239091 | 0.80 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL24207878 | 0.80 | CRBN (0.55) | CRBNDDB1 | |
| SCHEMBL30087084 | 0.80 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL31192256 | 0.80 | CRBN (0.46) | CRBNDDB1 | |
| SCHEMBL31068344 | 0.77 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL29348716 | 0.77 | CRBN (0.44) | CRBNDDB1 | |
| SCHEMBL24204588 | 0.76 | CRBN (0.46) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207267-A1 | (R)-Glutarimide CRBN Ligands and Methods of Use | BEIGENE SWITZERLAND GMBH (CH) | 2024-06-27 | — | — | US | disclosed |
| WO-2022268052-A9 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| WO-2022268052-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207267-A1 | (R)-Glutarimide CRBN Ligands and Methods of Use | CRBN, CDR2, CRKL | CRBN 1/4885DDB1 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.