Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487952 | 0.84 | MAPT (0.47) | GAASOS1ABL1HTTTSHR | |
| SCHEMBL31301254 | 0.84 | GAA (0.49) | GAASOS1ABL1HTTMEN1 | |
| SCHEMBL17118715 | 0.84 | MAPT (0.47) | GAASOS1ABL1HTTTSHR | |
| SCHEMBL20045541 | 0.81 | GAA (0.42) | GAASOS1ABL1HTTALDH1A1 | |
| SCHEMBL747498 | 0.81 | CA1 (0.49) | GAASOS1ABL1HTTTSHR | |
| SCHEMBL18703677 | 0.81 | GAA (0.46) | GAASOS1ABL1HTTALDH1A1 | |
| SCHEMBL8378560 | 0.80 | GAA (0.49) | GAASOS1ABL1HTTTSHR | |
| SCHEMBL12279551 | 0.80 | SOS1 (0.45) | GAASOS1ABL1HTTTSHR | |
| SCHEMBL24801995 | 0.79 | SOS1 (0.47) | GAASOS1HTTTSHRALDH1A1 | |
| SCHEMBL3337570 | 0.79 | SOS1 (0.47) | GAASOS1ABL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271679-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |