Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.56 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22343336 | 0.80 | TAAR1 (0.44) | TAAR1BACE1MEN1RAD52RECQL | |
| SCHEMBL15947157 | 0.79 | TAAR1 (0.67) | TAAR1BACE1MAPTHTR1AHTR1D | |
| SCHEMBL3205225 | 0.78 | GRIN2D (0.50) | TAAR1BACE1ALOX15GRIN2DGRIN3B | |
| SCHEMBL12797844 | 0.77 | GRIN2D (0.40) | TAAR1BACE1MEN1KMT2ATDP1 | |
| SCHEMBL11792898 | 0.77 | GRIN2D (0.40) | TAAR1BACE1MAPTALOX15GRIN2D | |
| SCHEMBL12082097 | 0.77 | GRIN2D (0.40) | TAAR1BACE1MEN1KMT2ATDP1 | |
| SCHEMBL13846533 | 0.75 | HTR2A (0.46) | TAAR1BACE1HTR2A | |
| SCHEMBL1046128 | 0.75 | BACE1 (0.50) | TAAR1BACE1MEN1RAD52RECQL | |
| SCHEMBL24422624 | 0.74 | TAAR1 (0.43) | TAAR1BACE1MEN1KMT2ATDP1 | |
| SCHEMBL5382583 | 0.74 | AR (0.39) | TAAR1BACE1MAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271982-A1 | SUBSTITUTED PHENETHYLAMINE FOR TREATING INFLAMMATION AND PSYCHOLOGICAL DISORDERS | SYNAPTIVE THERAPEUTICS, LLC (US) | 2022-12-29 | — | — | WO | disclosed |