Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084119 | 1.00 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL24811630 | 0.88 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL24810102 | 0.88 | LRRK2 (0.78) | LRRK2 | |
| SCHEMBL24809138 | 0.88 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL30084128 | 0.86 | LRRK2 (0.79) | LRRK2 | |
| SCHEMBL24810324 | 0.86 | LRRK2 (0.79) | LRRK2 | |
| SCHEMBL24811646 | 0.86 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL24810319 | 0.86 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL30084115 | 0.86 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL24809149 | 0.85 | LRRK2 (1.00) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271840-A1 | SELECTIVE INDAZOLE LRRK2 INHIBITORS AND METHODS FOR USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-12-29 | — | — | WO | disclosed |