Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25678537 | 0.88 | MEN1 (0.46) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL20572924 | 0.85 | USP2 (0.43) | SCN9ASMN1; SMN2 | |
| SCHEMBL30097332 | 0.85 | MEN1 (0.46) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL15874982 | 0.85 | MEN1 (0.46) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL27380633 | 0.85 | MEN1 (0.46) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL24810425 | 0.84 | SCN9A (0.38) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL27378695 | 0.84 | SCN9A (0.41) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL27377935 | 0.84 | SCN9A (0.41) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL31286870 | 0.83 | SCN9A (0.44) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL31286711 | 0.83 | SCN9A (0.44) | SCN9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272307-A1 | BIFUNCTIONAL FOLATE RECEPTOR BINDING COMPOUNDS | LYCIA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |