Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23569668 | 1.00 | NPC1 (0.33) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL23255179 | 0.90 | SMN1; SMN2 (0.33) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL26698297 | 0.79 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL23255184 | 0.77 | HSD17B3 (0.38) | SMN1; SMN2MAPTALDH1A1HPGDLMNA | |
| SCHEMBL19313202 | 0.77 | SMN1; SMN2 (0.37) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL21186552 | 0.76 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL21308092 | 0.74 | SMN1; SMN2 (0.35) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL24994576 | 0.74 | HSD17B3 (0.43) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL21066068 | 0.73 | MAPT (0.35) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL24865833 | 0.72 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022270549-A1 | NOVEL POLYMER-COATED CROSSLINKED ALGINATE GEL FIBER | 持田製薬株式会社 | 2022-12-29 | — | — | WO | disclosed |