Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 15/20 | 0.74 |
| ▸ | FAP | Q12884 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393452 | 1.00 | CYP3A4 (0.74) | CYP3A4FAPCYP2D6 | |
| SCHEMBL1393451 | 1.00 | CYP3A4 (0.74) | CYP3A4FAPCYP2D6 | |
| SCHEMBL10050006 | 0.90 | CYP3A4 (0.72) | CYP3A4FAPCYP2D6 | |
| SCHEMBL20644327 | 0.90 | CYP3A4 (0.61) | CYP3A4FAPCYP2D6 | |
| SCHEMBL28394178 | 0.89 | CYP3A4 (0.71) | CYP3A4FAPCYP2D6 | |
| SCHEMBL29389535 | 0.89 | CYP3A4 (0.71) | CYP3A4FAPCYP2D6 | |
| SCHEMBL19508635 | 0.89 | CYP3A4 (0.79) | CYP3A4FAPCYP2D6 | |
| SCHEMBL21986443 | 0.89 | CYP3A4 (0.79) | CYP3A4FAPCYP2D6 | |
| SCHEMBL15070860 | 0.89 | CYP3A4 (0.77) | CYP3A4FAPCYP2D6 | |
| SCHEMBL19470250 | 0.88 | CYP3A4 (0.73) | CYP3A4FAPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271880-A1 | METHODS OF TREATING MEDICAL CONDITIONS AND INHIBITING LINE1 REVERSE TRANSCRIPTASE USING A SUBSTITUTED ADENINYL-PROPYLOXY PHOSPHONIC ACID OR RELATED COMPOUND | ROME THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |