Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 17/20 | 0.43 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080287 | 0.86 | ATR (0.43) | MTORATRATRIPPIK3CA | |
| SCHEMBL24810137 | 0.83 | ATR (0.46) | MTORATRATRIP | |
| SCHEMBL24811148 | 0.82 | PDE2A (0.48) | MTORATRATRIP | |
| SCHEMBL25080796 | 0.81 | HRH3 (0.45) | MTORATRATRIP | |
| SCHEMBL25080710 | 0.81 | HRH3 (0.45) | MTORATRATRIP | |
| SCHEMBL25080270 | 0.79 | MTOR (0.48) | MTORATRATRIPPIK3CA | |
| SCHEMBL25080301 | 0.77 | MTOR (0.46) | MTORATRATRIPPIK3CA | |
| SCHEMBL25287138 | 0.77 | ATR (0.61) | MTORATRATRIPPIK3CA | |
| SCHEMBL25287137 | 0.77 | ATR (0.61) | MTORATRATRIPPIK3CA | |
| SCHEMBL25080627 | 0.77 | MTOR (0.46) | MTORATRATRIPPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268025-A1 | ATR INHIBITOR AND USE THEREOF | 成都苑东生物制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |