SCHEMBL24810985

SCHEMBL24810985

CN1CCC2(CC1)C[C@H](N[C@@H]1C[C@H]1c1ccccc1)CO2

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 20/20 0.60
MAOB P27338 6/20 0.48
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25455261 0.84 KDM1A (0.50) KDM1AMAOBMAOA
SCHEMBL25455077 0.84 KDM1A (0.55) KDM1AMAOBMAOA
SCHEMBL24811335 0.82 KDM1A (0.66) KDM1AMAOBMAOA
SCHEMBL24811331 0.82 KDM1A (0.66) KDM1AMAOBMAOA
SCHEMBL24811338 0.82 KDM1A (0.66) KDM1AMAOBMAOA
SCHEMBL24810984 0.82 KDM1A (0.66) KDM1AMAOBMAOA
SCHEMBL21843323 0.82 KDM1A (0.46) KDM1AMAOB
SCHEMBL23178092 0.82 KDM1A (0.51) KDM1A
SCHEMBL21843374 0.80 KDM1A (0.51) KDM1AMAOBMAOA
SCHEMBL21843308 0.80 EPHX2 (0.46) KDM1AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022267495-A1 NITROGEN-CONTAINING OXA-SPIROCYCLIC COMPOUND AND USE THEREOF 南昌弘益药业有限公司 2022-12-29 WO disclosed