SCHEMBL2481213

SCHEMBL2481213

Cc1cc2c(cc1C(F)(F)F)N(OC(=O)OC(C)(C)C)CCC[C@@H]2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2479637 0.92 CETP (0.56) CETP
SCHEMBL2478247 0.92 CETP (0.53) CETP
SCHEMBL2479075 0.91 CETP (0.54) CETP
SCHEMBL2478924 0.91 CETP (0.57) CETP
SCHEMBL1377834 0.89 CETP (0.54) CETP
SCHEMBL2480503 0.89 CETP (0.52) CETP
SCHEMBL2476250 0.89 CETP (0.54) CETP
SCHEMBL2477112 0.88 CETP (0.53) CETP
SCHEMBL2475998 0.86 CETP (0.54) CETP
SCHEMBL2475991 0.86 CETP (0.54) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761522-B1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA LILLY CO ELI (US) 2011-10-12 EP claimed