SCHEMBL2481237

SCHEMBL2481237

Cn1c(=O)cc2c3c(c(N)ccc31)C(=O)c1ccccc1-2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 5/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ MEN1 O00255 8/20 0.62
▸ KMT2A Q03164 8/20 0.62
▸ MAPT P10636 6/20 0.62
▸ POLB P06746 5/20 0.62
▸ L3MBTL1 Q9Y468 4/20 0.62
▸ THRB P10828 2/20 0.62
▸ MAPK1 P28482 2/20 0.62
▸ TDP1 Q9NUW8 2/20 0.62
▸ NSD2 O96028 1/20 0.62
▸ S100A4 P26447 1/20 0.62
▸ NR4A1 P22736 1/20 0.56
▸ SMN1; SMN2 Q16637 4/20 0.55
▸ PABPC1 P11940 3/20 0.55
▸ CSNK1A1 P48729 2/20 0.50
▸ CSNK1D P48730 2/20 0.50
▸ CSNK1G1 Q9HCP0 2/20 0.50
▸ MAOA P21397 2/20 0.50
▸ FGR P09769 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2483117 0.83 CYP1A2 (0.71) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL13295898 0.81 CYP1A2 (0.67) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL12311502 0.78 NR4A1 (0.79) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL14422840 0.77 MAPT (1.00) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL16261316 0.75 ADORA2A (0.60) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL12311433 0.75 CYP1A2 (0.59) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL12311501 0.75 NR4A1 (0.71) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL12311514 0.75 NR4A1 (0.65) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL29384913 0.75 NR4A1 (0.78) ADORA2ACYP1A2MEN1KMT2AMAPT
SCHEMBL305199 0.75 NR4A1 (0.78) ADORA2ACYP1A2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9519079-B2 Coloring composition, colored pattern, color filter and method of producing the same, pattern forming method, solid-state imaging device, and image display device FUJIFILM CORPORATION (JP) 2016-12-13 — — US disclosed
US-9519079-B2 Coloring composition, colored pattern, color filter and method of producing the same, pattern forming method, solid-state imaging device, and image display device FUJIFILM CORPORATION (JP) 2016-12-13 — — US disclosed
US-9470974-B2 Coloring composition, coloring radiation-sensitive composition, color filter and solid-state imaging device FUJIFILM CORPORATION (JP) 2016-10-18 — — US disclosed
US-9470974-B2 Coloring composition, coloring radiation-sensitive composition, color filter and solid-state imaging device FUJIFILM CORPORATION (JP) 2016-10-18 — — US disclosed
US-9268063-B2 Colored radiation-sensitive composition, colored cured film, color filter, colored pattern forming method, color filter production method, solid-state image sensor, and image display device FUJIFILM CORPORATION (JP) 2016-02-23 — — US disclosed
US-9268063-B2 Colored radiation-sensitive composition, colored cured film, color filter, colored pattern forming method, color filter production method, solid-state image sensor, and image display device FUJIFILM CORPORATION (JP) 2016-02-23 — — US disclosed
US-20150268246-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2015-09-24 — — US disclosed
US-20150268246-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2015-09-24 — — US disclosed
US-20150268246-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2015-09-24 — — US disclosed
US-9081273-B2 Radiation-sensitive colored composition, color filter, method for producing a color pattern, method for producing color filter, solid-state imaging device, and liquid crystal display apparatus FUJIFILM CORPORATION (JP) 2015-07-14 — — US disclosed
US-20120202145-A1 RADIATION-SENSITIVE COLORED COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME, SOLID STATE IMAGE DEVICE, AND LIQUID CRYSTAL DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2012-08-09 — — US disclosed
EP-2057123-B1 ANTHRAPYRIDONE COMPOUNDS SABIC INNOVATIVE PLASTICS IP (NL) 2011-10-19 — — EP disclosed
US-7812076-B2 Anthrapyridone compounds SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-10-12 — — US disclosed
EP-2057123-A1 ANTHRAPYRIDONE COMPOUNDS Sabic Innovative Plastics IP B.V. (NL) 2009-05-13 — — EP disclosed
US-20080076188-A1 Luminescent compounds SETA BIOMEDICALS, LLC 2008-03-27 — — US disclosed
US-20080076188-A1 Luminescent compounds SETA BIOMEDICALS, LLC 2008-03-27 — — US disclosed
US-20080076188-A1 Luminescent compounds SETA BIOMEDICALS, LLC 2008-03-27 — — US disclosed
US-20080045634-A1 ANTHRAPYRIDONE COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2008-02-21 — — US disclosed
WO-2008021694-A1 ANTHRAPYRIDONE COMPOUNDS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-02-21 — — WO disclosed
US-7211131-B2 Phase change inks XEROX CORPORATION (US) 2007-05-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076188-A1 Luminescent compounds REL, QRFPR, RCOR3 ADORA2A 2034/4885CYP1A2 1452/4885MEN1 3074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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