Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 15/20 | 0.60 |
| ▸ | BRAF | P15056 | 1/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.55 |
| ▸ | MTOR | P42345 | 4/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24812407 | 0.89 | ATR (0.65) | ATRBRAFPIK3CAMTORPIK3CD | |
| SCHEMBL24811616 | 0.81 | ATR (0.71) | ATRBRAFPIK3CAMTORPIK3CD | |
| SCHEMBL24811195 | 0.81 | ATR (0.57) | ATRBRAFATRIP | |
| SCHEMBL24810115 | 0.80 | ATR (0.58) | ATRBRAFPIK3CAMTORPIK3CD | |
| SCHEMBL24812436 | 0.79 | ATR (0.56) | ATRBRAFATRIP | |
| SCHEMBL24811608 | 0.78 | ATR (0.67) | ATRBRAFPIK3CAMTORPIK3CD | |
| SCHEMBL24811617 | 0.78 | ATR (0.80) | ATRBRAFATRIP | |
| SCHEMBL24811614 | 0.77 | ATR (0.73) | ATRBRAFMTORATRIP | |
| SCHEMBL29805950 | 0.77 | ATR (0.73) | ATRBRAFMTORATRIP | |
| SCHEMBL24811619 | 0.76 | ATR (0.70) | ATRBRAFATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268025-A1 | ATR INHIBITOR AND USE THEREOF | 成都苑东生物制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |