Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.53 |
| ▸ | KDM5A | P29375 | 9/20 | 0.53 |
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821182 | 1.00 | KDM4C (0.53) | KDM4CKDM5APAOXPHF8KDM4A | |
| SCHEMBL12446965 | 0.98 | KDM4C (0.55) | KDM4CKDM5APAOXPHF8KDM4A | |
| SCHEMBL3415138 | 0.91 | KDM5A (0.47) | KDM4CKDM5APAOXPHF8KDM5C | |
| SCHEMBL9265588 | 0.83 | KDM4C (0.68) | KDM4CKDM5APHF8KDM4AALDH1A1 | |
| SCHEMBL12051216 | 0.83 | KDM4C (0.68) | KDM4CKDM5APHF8KDM4AALDH1A1 | |
| SCHEMBL24359505 | 0.83 | PAOX (0.48) | KDM4CKDM5APAOXPHF8KDM4A | |
| SCHEMBL14473377 | 0.83 | KDM4C (0.56) | KDM4CKDM5APAOXPHF8KDM4A | |
| SCHEMBL14085585 | 0.81 | — | — | |
| SCHEMBL6820435 | 0.80 | PAOX (0.72) | KDM4CKDM5APAOXPHF8ALDH1A1 | |
| SCHEMBL12248451 | 0.79 | PAOX (0.70) | KDM4CKDM5APAOXPHF8KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |