SCHEMBL24812686

SCHEMBL24812686

C[C@H](CC(=O)N1CCC(O)(Cn2cnn3c(N)ccc3c2=O)CC1)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 19/20 0.69
USP19 O94966 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17868534 0.90 USP7 (0.72) USP7USP19
SCHEMBL24812611 0.90 USP7 (0.70) USP7USP19
SCHEMBL24811156 0.89 USP7 (0.69) USP7USP19
SCHEMBL24811538 0.89 USP7 (0.69) USP7USP19
SCHEMBL24812612 0.89 USP7 (0.69) USP7USP19
SCHEMBL24811406 0.89 USP7 (0.69) USP7USP19
SCHEMBL24812613 0.89 USP7 (0.68) USP7USP19
SCHEMBL24812555 0.85 USP7 (0.63) USP7USP19
SCHEMBL24811553 0.84 USP7 (0.65) USP7USP19
SCHEMBL17868408 0.84 USP7 (0.76) USP7USP19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272133-A2 PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS Stablix, Inc. (US) 2022-12-29 WO disclosed