Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 8/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075644 | 0.98 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2TP53HPGD | |
| SCHEMBL26412077 | 0.88 | MEN1 (0.47) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL16674308 | 0.88 | KMT2A (0.53) | KMT2AMEN1SMN1; SMN2TP53HPGD | |
| SCHEMBL25791386 | 0.86 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2TP53HPGD | |
| SCHEMBL20223530 | 0.86 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL25812337 | 0.86 | MEN1 (0.46) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL23386933 | 0.86 | MEN1 (0.50) | KMT2AMEN1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL23665082 | 0.86 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2TP53HPGD | |
| SCHEMBL22054928 | 0.86 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2TP53HPGD | |
| SCHEMBL18908667 | 0.86 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |