SCHEMBL24813115

SCHEMBL24813115

Cc1nnc2nc(N(CC(F)F)c3cc(F)cc(C#CC4COC4)c3)c3c(F)cccc3n12

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30047923 1.00 PTAFR (0.30) PTAFR
SCHEMBL29909929 0.93 PTAFR (0.31) PTAFR
SCHEMBL23577544 0.93 PTAFR (0.31) PTAFR
SCHEMBL30049529 0.93
SCHEMBL24814621 0.86
SCHEMBL30047986 0.86
SCHEMBL24813116 0.85 PTAFR (0.31) PTAFR
SCHEMBL29909230 0.85 PTAFR (0.31) PTAFR
SCHEMBL23576630 0.85 PTAFR (0.31) PTAFR
SCHEMBL23577968 0.84 PTAFR (0.32) PTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022271684-A1 DIACYLGLYERCOL KINASE MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-12-29 WO disclosed