SCHEMBL2481325

SCHEMBL2481325

CC(C)OC(=O)ON1CCC[C@H](N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(CCO)n2)c2cc3c(cc21)CCC3

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2480093 0.92 CETP (0.58) CETP
SCHEMBL2479945 0.92 CETP (0.58) CETP
SCHEMBL2479705 0.91 CETP (0.58) CETP
SCHEMBL2476100 0.90 CETP (0.61) CETP
SCHEMBL2476099 0.90 CETP (0.61) CETP
SCHEMBL2473283 0.89 CETP (0.55) CETP
SCHEMBL2479141 0.87 CETP (0.56) CETP
SCHEMBL2478216 0.86 CETP (0.54) CETP
SCHEMBL2477120 0.85 CETP (0.57) CETP
SCHEMBL2480503 0.83 CETP (0.52) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761522-B1 COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA LILLY CO ELI (US) 2011-10-12 EP claimed