Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29144184 | 1.00 | TNF (0.49) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL30049141 | 1.00 | TNF (0.49) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7858417 | 0.89 | TNF (0.58) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL29299744 | 0.87 | TNF (0.49) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL2280493 | 0.86 | TNF (0.47) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL2278593 | 0.86 | TNF (0.47) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL24816171 | 0.86 | TNF (0.45) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL24814978 | 0.86 | TNF (0.45) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL20294609 | 0.85 | TNF (0.45) | TNFALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL28370724 | 0.85 | TNF (0.45) | TNFALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425642-A | Preparation method of (S) -2- (2, 6-dioxopiperidine-3-yl) -4- ((2-fluoro-4- ((3-morpholinoazetidin-1-yl) methyl) benzyl) amino) isoindoline-1, 3-dione | 新基公司 | 2024-01-19 | — | — | CN | disclosed |
| WO-2022271557-A1 | PROCESSES FOR THE PREPARATION OF (S)-2-(2,6-DIOXOPIPERIDIN-3-YL)-4-((2-FLUORO-4-((3-MORPHOLINOAZETIDIN-1-YL) METHYL)BENZYL) AMINO)ISOINDOLINE-1,3-DIONE | CELGENE CORPORATION (US) | 2022-12-29 | — | — | WO | disclosed |