Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481354 | 0.84 | PTGDR2 (0.71) | PTGDR2 | |
| SCHEMBL2482601 | 0.71 | PTGDR2 (0.79) | PTGDR2 | |
| SCHEMBL2483814 | 0.71 | PTGDR2 (0.72) | PTGDR2 | |
| SCHEMBL2485193 | 0.70 | PTGDR2 (0.81) | PTGDR2 | |
| SCHEMBL2480767 | 0.70 | PTGDR2 (0.87) | PTGDR2 | |
| SCHEMBL2482425 | 0.68 | PTGDR2 (0.86) | PTGDR2 | |
| SCHEMBL2483463 | 0.67 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2481862 | 0.67 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2483474 | 0.67 | PTGDR2 (1.00) | PTGDR2 | |
| SCHEMBL2485748 | 0.67 | PTGDR2 (0.69) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891075-B1 | TRICYCLIC SPIRO DERIVATIVES AS CRTH2 MODULATORS | MERCK SERONO SA (CH) | 2011-10-19 | — | — | EP | disclosed |