Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30047933 | 1.00 | TNKS (0.32) | TNKSPARP1TNKS2CYP19A1CYP2C9 | |
| SCHEMBL23601783 | 0.84 | PTAFR (0.30) | — | |
| SCHEMBL23601784 | 0.83 | PDE2A (0.31) | — | |
| SCHEMBL23576980 | 0.82 | TNIK (0.32) | — | |
| SCHEMBL29909432 | 0.82 | TNIK (0.32) | — | |
| SCHEMBL29909140 | 0.82 | — | — | |
| SCHEMBL23577035 | 0.82 | — | — | |
| SCHEMBL29909062 | 0.82 | — | — | |
| SCHEMBL23601470 | 0.79 | PTAFR (0.31) | — | |
| SCHEMBL23601467 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271684-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |