Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815588 | 0.75 | DPP7 (0.41) | — | |
| SCHEMBL18925624 | 0.74 | CHRNA7 (0.32) | CHRNA7 | |
| SCHEMBL16229278 | 0.72 | CHRNA7 (0.36) | CHRNA7KDM4EALDH1A1MAPT | |
| SCHEMBL24943289 | 0.72 | CHRNA7 (0.33) | CHRNA7 | |
| SCHEMBL24815569 | 0.71 | SETD7 (0.39) | — | |
| SCHEMBL22306151 | 0.71 | CHRNA7 (0.43) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL24816956 | 0.70 | CHRNA7 (0.47) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL104677 | 0.69 | — | — | |
| SCHEMBL24496310 | 0.69 | CHRNA7 (0.42) | CHRNA7KDM4EALDH1A1MAPTPKM | |
| SCHEMBL57304 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268230-A1 | COMPOUND AS KIF18A INHIBITOR | 杭州英创医药科技有限公司 | 2022-12-29 | — | — | WO | disclosed |