Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24815663 | 0.85 | GPR183 (0.35) | GPR183KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL24816948 | 0.80 | KDM4E (0.36) | GPR183KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL24816950 | 0.77 | KDM4E (0.34) | GPR183KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL12685137 | 0.72 | GRIA1 (0.39) | GPR183KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL12469211 | 0.72 | GRIA1 (0.39) | GPR183KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL4745100 | 0.72 | GRIA1 (0.39) | GPR183KDM4EGRIA1GRIA2GRIA3 | |
| SCHEMBL15348806 | 0.72 | KDM4E (0.42) | GPR183KDM4EHRH3MEN1KMT2A | |
| SCHEMBL11575106 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL3734569 | 0.71 | GRIA1 (0.38) | GPR183KDM4EGRIA1GRIA2GRIA3 | |
| Bromide SCHEMBL3737234 | 0.71 | GRIA1 (0.38) | GPR183KDM4EGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268230-A1 | COMPOUND AS KIF18A INHIBITOR | 杭州英创医药科技有限公司 | 2022-12-29 | — | — | WO | disclosed |