⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL188146 | 1.00 | — | — | |
| Phosphine SCHEMBL28551397 | 1.00 | — | — | |
| Phosphine SCHEMBL15525085 | 1.00 | — | — | |
| Phosphine SCHEMBL3166267 | 1.00 | — | — | |
| Methane SCHEMBL28870772 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL1900485 | 0.82 | — | — | |
| Phosphine SCHEMBL5693061 | 0.82 | — | — | |
| Phosphine SCHEMBL165123 | 0.82 | — | — | |
| Phosphine SCHEMBL11076631 | 0.82 | — | — | |
| Phosphine SCHEMBL5682224 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462395-A | Synthesis method of chiral indene amine | 中国科学院大连化学物理研究所 | 2025-02-18 | — | — | CN | claimed |
| CN-118206454-A | Synthesis and application of chiral (2R, 5R) -2, 5-hexamethylenediamine | 中国科学院大连化学物理研究所 | 2024-06-18 | — | — | CN | claimed |
| WO-2022193806-A1 | METHOD FOR ASYMMETRIC CATALYTIC SYNTHESIS OF NICOTINE | 凯特立斯（深圳）科技有限公司 | 2022-09-22 | — | — | WO | claimed |
| US-20220017451-A1 | PREPARATION OF CHIRAL PRIMARY AMINE FROM ASYMMETRIC REDUCTIVE AMINATION OF SIMPLE KETONE CATALYZED BY RUTHENIUM-DIPHOSPHINE CATALYST | SHENZHEN CATALYS TECHNOLOGY CO., LTD (CN) | 2022-01-20 | — | — | US | claimed |
| CN-105001098-B | A kind of preparation method of 3 (R)/(S)-amino-n-butyl alcohol | 嵊州市油脂化工有限公司 | 2016-09-14 | — | — | CN | claimed |
| CN-104961640-B | A kind of preparation method of optically pure 3-amino-n-butyl alcohol | 嵊州市油脂化工有限公司 | 2016-09-07 | — | — | CN | claimed |
| US-20100179323-A1 | PROCESS FOR MAKING DIPHOSPINE-RUTHENIUM-DIAMINE COMPLEXES | DR. REDDY'S LABORATORIES LIMITED (IN) | 2010-07-15 | — | — | US | claimed |
| EP-1902061-B1 | PROCESS FOR MAKING DIPHOSPHINE-RUTHENIUM-DIAMINE COMPLEXES | REDDY S LAB EU LTD DR (GB) | 2009-12-30 | — | — | EP | claimed |
| CN-101208350-A | Process for making diphosphine-ruthenium-diamine complexes | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-06-25 | — | — | CN | claimed |
| EP-1902061-A1 | PROCESS FOR MAKING DIPHOSPHINE-RUTHENIUM-DIAMINE COMPLEXES | Dow Gloval Technologies Inc. (US) | 2008-03-26 | — | — | EP | claimed |
| EP-0570764-B1 | Asymmetric hydrogenation | HOFFMANN LA ROCHE (CH) | 2001-07-18 | — | — | EP | claimed |
| CN-1053902-C | Hydrogenation process | HOFFMANN LA ROCHE (CH) | 2000-06-28 | — | — | CN | claimed |
| US-6069245-A | PRODUCING A 3-BENZOYLAMINO-4-BENZOYLOXYHEXAHYDROAZEPINE BY THE CATALYTIC HYDROGENATION OF THE 4-OXO-AMINE SALT DERIVATIVE; PROTECTING THE RING NITROGEN; FORMING A FUSED RING; HYDROLYSIS; ACYLATION AND DEPROTECTING | HOFFMANN-LA ROCHE INC. (US) | 2000-05-30 | — | — | US | claimed |
| EP-0787711-B1 | Process for the preparation of alpha,beta-unsaturated carboxylic acids | HOFFMANN LA ROCHE (CH) | 2000-04-26 | — | — | EP | claimed |
| US-6013833-A | USING A CATALYST OF A COMPLEX OF RUTHENIUM AND AN OPTICALLY ACTIVE PHOSPHINE; PRODUCING (R)-3-HYDROXYOCTANEDIOIC ACID DIESTERS AS CHEMICAL INTERMEDIATES OF ALPHA-LIPOIC ACID | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2000-01-11 | — | — | US | claimed |
| US-5919962-A | CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-07-06 | — | — | US | claimed |
| US-5902882-A | ASYMMETRICALLY HYDROGENATING AN AZEPINE COMPOUND IN THE PRESENCE OF A RUTHENIUM-DIPHOSPHINE COMPLEX CATALYST | HOFFMANN-LA ROCHE INC. (US) | 1999-05-11 | — | — | US | claimed |
| US-5750690-A | HYDROGENATION OF A 1,2-DIALKYLOXO-3-CARBOXY-3-PYRAZOLINE OR 1,2,5,6-TETRAHYDROPYRIDAZINE OR DERIVATIVE; INTERMEDIATES FOR THE HYPOTENSIVE AGENT, ?CILAZAPRIL? | HOFFMANN-LA ROCHE INC. (US) | 1998-05-12 | — | — | US | claimed |
| EP-0512415-B1 | Process for the enantioselective synthesis of 2(R)-benzyl succanamide derivatives | HOECHST AG (DE) | 1997-08-06 | — | — | EP | claimed |
| EP-0643052-B1 | Process for enantioselective hydrogenation of 2H-Pyran-2-one derivatives | HOFFMANN LA ROCHE (CH) | 1996-12-18 | — | — | EP | claimed |