Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960306 | 0.95 | BCL2 (0.70) | BCL2BCL2L1 | |
| SCHEMBL1960390 | 0.91 | BCL2 (0.64) | BCL2BCL2L1 | |
| SCHEMBL1745338 | 0.88 | BCL2 (0.68) | BCL2BCL2L1 | |
| SCHEMBL1742803 | 0.88 | BCL2 (0.69) | BCL2BCL2L1 | |
| SCHEMBL1958202 | 0.87 | BCL2 (0.62) | BCL2BCL2L1 | |
| SCHEMBL1957079 | 0.86 | BCL2 (0.66) | BCL2BCL2L1 | |
| SCHEMBL1957207 | 0.86 | BCL2 (0.64) | BCL2BCL2L1 | |
| SCHEMBL1958793 | 0.85 | BCL2 (0.66) | BCL2BCL2L1 | |
| SCHEMBL1960056 | 0.84 | BCL2 (0.70) | BCL2BCL2L1 | |
| SCHEMBL1956825 | 0.84 | BCL2 (0.64) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376197-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010065824-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |