⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16387222 | 0.70 | GRIN2D (0.59) | — | |
| SCHEMBL17586278 | 0.67 | — | — | |
| SCHEMBL24618878 | 0.67 | — | — | |
| SCHEMBL16448446 | 0.65 | GRIN2D (0.30) | — | |
| Hydrochloric Acid SCHEMBL25371732 | 0.65 | GRIN2D (0.50) | — | |
| SCHEMBL24086615 | 0.65 | GRIN2D (0.30) | — | |
| SCHEMBL25046444 | 0.63 | — | — | |
| SCHEMBL24117639 | 0.63 | GRIN2D (0.32) | — | |
| SCHEMBL23564483 | 0.61 | GRIN2D (0.32) | — | |
| SCHEMBL17675827 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912686-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230212151-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
| US-11584738-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220411406-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2022-12-29 | — | — | US | disclosed |