Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30260152 | 0.90 | ESR2 (0.64) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL21470912 | 0.90 | ESR2 (0.64) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL30199587 | 0.90 | ESR2 (0.64) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL23684302 | 0.90 | ESR2 (0.64) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL17221201 | 0.84 | HDAC1 (0.49) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL3876257 | 0.84 | NR1H2 (0.48) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL23727707 | 0.82 | NR1H2 (0.47) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL29835115 | 0.82 | NR1H2 (0.47) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL21470913 | 0.82 | ESR2 (0.43) | ESR2NR1H2HDAC1DDB1CRBN | |
| SCHEMBL23727210 | 0.81 | HDAC1 (0.47) | ESR2NR1H2HDAC1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |