Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 6/20 | 0.66 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.64 |
| ▸ | IKZF3 | Q9UKT9 | 14/20 | 0.64 |
| ▸ | IL1B | P01584 | 3/20 | 0.59 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816895 | 0.95 | TNF (0.72) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL25134008 | 0.91 | TNF (0.74) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL26364233 | 0.90 | CRBN (0.65) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL23325661 | 0.90 | TNF (0.77) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL22959760 | 0.88 | TNF (0.65) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL24818132 | 0.88 | CRBN (0.60) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL26364226 | 0.87 | CRBN (0.66) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL22959645 | 0.85 | TNF (0.71) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL26366746 | 0.85 | TNF (0.68) | TNFCRBNIKZF3IL1BIKZF1 | |
| SCHEMBL24590687 | 0.85 | CRBN (0.70) | TNFCRBNIKZF3IL1BIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |