Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.53 |
| ▸ | IKZF2 | Q9UKS7 | 3/20 | 0.49 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24817924 | 0.94 | CRBN (0.54) | CRBNIKZF2IKZF1IKZF3 | |
| SCHEMBL20046850 | 0.89 | CRBN (0.52) | CRBNIKZF2IKZF1CSNK1A1IKZF3 | |
| SCHEMBL25010545 | 0.87 | CRBN (0.60) | CRBNIKZF2IKZF1 | |
| SCHEMBL24742723 | 0.84 | CRBN (0.54) | CRBNIKZF2IKZF1CSNK1A1IKZF3 | |
| SCHEMBL30122023 | 0.84 | CRBN (0.54) | CRBNIKZF2IKZF1CSNK1A1IKZF3 | |
| SCHEMBL24817722 | 0.83 | CRBN (0.61) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30270874 | 0.82 | CRBN (0.63) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL24745083 | 0.82 | CRBN (0.63) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL31204533 | 0.82 | CRBN (0.60) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL20231502 | 0.82 | CRBN (0.60) | CRBNIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |