Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248271 | 0.96 | PIK3CA (0.51) | PIK3CAPIK3CD | |
| SCHEMBL246449 | 0.90 | PIK3CA (0.49) | PIK3CAPIK3CD | |
| SCHEMBL248991 | 0.88 | PIK3CA (0.45) | PIK3CAPIK3CD | |
| SCHEMBL247505 | 0.87 | PIK3CA (0.47) | PIK3CAPIK3CD | |
| SCHEMBL245634 | 0.87 | PIK3CA (0.47) | PIK3CAPIK3CD | |
| SCHEMBL248796 | 0.82 | PIK3CA (0.53) | PIK3CAPIK3CD | |
| SCHEMBL245564 | 0.81 | PIK3CD (0.42) | PIK3CAPIK3CD | |
| SCHEMBL247498 | 0.80 | PIK3CA (0.53) | PIK3CAPIK3CD | |
| SCHEMBL247889 | 0.80 | PIK3CA (0.49) | PIK3CAPIK3CD | |
| SCHEMBL248910 | 0.79 | PIK3CA (0.51) | PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588471-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY | Amgen Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| WO-2012003283-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY | AMGEN INC. (US) | 2012-01-05 | — | — | WO | disclosed |