Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.66 |
| ▸ | INSR | P06213 | 10/20 | 0.66 |
| ▸ | IGF1R | P08069 | 10/20 | 0.66 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.62 |
| ▸ | ROS1 | P08922 | 1/20 | 0.62 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24817865 | 0.91 | ALK (0.71) | ALKINSRIGF1RMAP4K1EGFR | |
| SCHEMBL24816643 | 0.89 | MAP4K1 (0.67) | ALKINSRIGF1RMAP4K1EGFR | |
| SCHEMBL24817991 | 0.89 | ALK (0.76) | ALKINSRIGF1RMAP4K1AURKA | |
| SCHEMBL24817939 | 0.88 | ALK (0.84) | ALKINSRIGF1RMAP4K1AURKA | |
| SCHEMBL24816811 | 0.88 | ALK (0.72) | ALKINSRIGF1RAURKAROS1 | |
| SCHEMBL22493313 | 0.87 | ALK (0.84) | ALKINSRIGF1RAURKAROS1 | |
| SCHEMBL30090750 | 0.87 | ALK (0.84) | ALKINSRIGF1RAURKAROS1 | |
| SCHEMBL24818182 | 0.87 | ALK (0.68) | ALKINSRIGF1RMAP4K1AURKA | |
| SCHEMBL24819291 | 0.86 | ALK (0.69) | ALKINSRIGF1RMAP4K1EGFR | |
| SCHEMBL24816828 | 0.85 | ALK (0.78) | ALKINSRIGF1RMAP4K1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |