Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 12/20 | 0.48 |
| ▸ | TNF | P01375 | 6/20 | 0.45 |
| ▸ | IL1B | P01584 | 3/20 | 0.41 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257874 | 0.85 | CRBN (0.55) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30262834 | 0.84 | CRBN (0.51) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31601560 | 0.81 | CRBN (0.41) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL21997441 | 0.80 | CRBN (0.48) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL23739524 | 0.80 | CRBN (0.73) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31023064 | 0.80 | CRBN (0.50) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL24160836 | 0.78 | CRBN (0.50) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL12041906 | 0.78 | CRBN (0.61) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL23355848 | 0.78 | CRBN (0.50) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL21997269 | 0.78 | CRBN (0.62) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268229-A1 | PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE | 和径医药科技（上海）有限公司 | 2022-12-29 | — | — | WO | disclosed |