Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 16/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153087 | 1.00 | CBLB (0.41) | CBLBS1PR1CYP3A4CYP2D6TSHR | |
| SCHEMBL24818752 | 0.96 | CBLB (0.36) | CBLBS1PR1CYP3A4VSIRS1PR3 | |
| SCHEMBL30152599 | 0.96 | CBLB (0.36) | CBLBS1PR1CYP3A4VSIRS1PR3 | |
| SCHEMBL24819886 | 0.89 | CBLB (0.35) | CBLBS1PR1VSIRS1PR3 | |
| SCHEMBL24819884 | 0.85 | PDCD1 (0.43) | CBLBS1PR1VSIRS1PR3 | |
| SCHEMBL24822059 | 0.85 | PDCD1 (0.43) | CBLBS1PR1VSIRS1PR3 | |
| SCHEMBL24818755 | 0.85 | GRM2 (0.38) | CBLBS1PR1S1PR3 | |
| SCHEMBL24819893 | 0.85 | CBLB (0.40) | CBLBS1PR1S1PR3 | |
| SCHEMBL24818677 | 0.85 | CBLB (0.40) | CBLBS1PR1S1PR3 | |
| SCHEMBL24818829 | 0.85 | CBLB (0.42) | CBLBS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |