Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 3/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 7/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24820573 | 1.00 | CBLB (0.34) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL24818652 | 1.00 | CBLB (0.34) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL30152822 | 1.00 | CBLB (0.34) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL30152831 | 1.00 | CBLB (0.34) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL30152583 | 1.00 | CBLB (0.34) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL24819902 | 0.93 | CBLB (0.34) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL30152644 | 0.93 | CBLB (0.34) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL24819974 | 0.91 | CBLB (0.44) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL30152790 | 0.91 | CBLB (0.44) | CBLBTRPV3CD274PDCD1PDCD1LG2 | |
| SCHEMBL30152993 | 0.91 | CBLB (0.44) | CBLBTRPV3CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |