SCHEMBL24819032

SCHEMBL24819032

COC[C@H](C)NCc1cc(C)c2oc(-c3cc(-c4ccc(F)cc4-c4nncn4C)cc(C4CC4)n3)nc2c1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30152960 1.00 CBLB (0.34) CBLB
SCHEMBL30152998 1.00 CBLB (0.34) CBLB
SCHEMBL24821811 1.00 CBLB (0.34) CBLB
SCHEMBL24821965 0.95 CBLB (0.34) CBLB
SCHEMBL31578966 0.95 CBLB (0.34) CBLB
SCHEMBL31578913 0.95 CBLB (0.34) CBLB
SCHEMBL24819022 0.95 CBLB (0.34) CBLB
SCHEMBL24821964 0.95 CBLB (0.34) CBLB
SCHEMBL24819064 0.91 CBLB (0.34) CBLB
SCHEMBL24820596 0.91 CBLB (0.34) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272248-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2022-12-29 — — WO disclosed
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