Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 14/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152715 | 1.00 | CBLB (0.41) | CBLBCNR2PDCD1CD274S1PR1 | |
| SCHEMBL30152755 | 1.00 | CBLB (0.41) | CBLBCNR2PDCD1CD274S1PR1 | |
| SCHEMBL24820255 | 1.00 | CBLB (0.41) | CBLBCNR2PDCD1CD274S1PR1 | |
| SCHEMBL29189932 | 1.00 | CBLB (0.41) | CBLBCNR2PDCD1CD274S1PR1 | |
| SCHEMBL30152918 | 0.93 | CBLB (0.38) | CBLBPDCD1CD274PDE2A | |
| SCHEMBL24818957 | 0.93 | CBLB (0.38) | CBLBPDCD1CD274PDE2A | |
| SCHEMBL24818788 | 0.90 | CBLB (0.44) | CBLBCNR2PDCD1CD274S1PR1 | |
| SCHEMBL24819900 | 0.90 | CBLB (0.44) | CBLBCNR2PDCD1CD274S1PR1 | |
| SCHEMBL30153015 | 0.90 | CBLB (0.44) | CBLBCNR2PDCD1CD274S1PR1 | |
| SCHEMBL30152952 | 0.90 | CBLB (0.44) | CBLBCNR2PDCD1CD274S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |