Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24821309 | 0.89 | NTRK1 (0.42) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24821270 | 0.87 | HDAC3 (0.45) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24822535 | 0.86 | NTRK1 (0.43) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24821298 | 0.85 | HDAC3 (0.52) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24821363 | 0.83 | MARK4 (0.55) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24821290 | 0.80 | HDAC6 (0.49) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24822571 | 0.78 | HDAC3 (0.47) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24821153 | 0.76 | HDAC3 (0.45) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24822555 | 0.75 | POLB (0.44) | TP53HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24823218 | 0.73 | HDAC6 (0.53) | HDAC3HDAC1HDAC2HDAC6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268066-A1 | PROTEIN DEGRADATION AGENT | 苏州开拓药业股份有限公司 | 2022-12-29 | — | — | WO | disclosed |