SCHEMBL248228

SCHEMBL248228

[CH]1COO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140409 0.76
SCHEMBL25274857 0.73
SCHEMBL1190870 0.67
SCHEMBL2554291 0.62
SCHEMBL30378180 0.59
SCHEMBL21330743 0.59
SCHEMBL23964 0.54
SCHEMBL15874999 0.54
SCHEMBL8853909 0.47
SCHEMBL41660 0.47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 691 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190869-A1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES PFIZER (US) 2024-06-13 US claimed
US-20240182416-A1 DERIVATIVES OF ARYL HYDROCARBON RECEPTOR AGONISTS AZORA THERAPEUTICS, INC. 2024-06-06 US claimed
US-11834412-B2 Derivatives of aryl hydrocarbon receptor agonists AZORA THERAPEUTICS, INC. (US) 2023-12-05 US claimed
CN-220082240-U Steam pressure reducing valve with good rust prevention effect 大连驰恒系统控制技术有限公司 2023-11-24 CN claimed
US-20230192690-A1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES PFIZER (US) 2023-06-22 US claimed
WO-2023077216-A1 HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS FOR TREATING FUNGAL INFECTIONS AND METHODS OF USE THEREOF BRIGHT ANGEL THERAPEUTICS INC. (CA) 2023-05-11 WO claimed
US-20220204484-A1 CHEMICAL INHIBITION OF THE E3 LIGASE SUBUNIT FBXO7 CONFERS NEUROPROTECTION AND ANTI-INFLAMMATORY ACTIVITY BY STABILIZING MITOCHONDRIA UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-06-30 US claimed
US-11242339-B2 Chemical inhibition of the E3 ligase subunit FBXO7 confers neuroprotection and anti-inflammatory activity by stabilizing mitochondria University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-02-08 US claimed
US-20210309659-A1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES PFIZER (US) 2021-10-07 US claimed
US-20210198235-A1 DERIVATIVES OF PIPERLONGUMINE AND USES THEREOF AURANSA INC. 2021-07-01 US claimed
WO-2018234953-A1 DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES PFIZER INC. (US) 2018-12-27 WO claimed
WO-2018175385-A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF PARASITIC DISEASES THE BROAD INSTITUTE, INC. (US) 2018-09-27 WO claimed
US-20180002331-A1 5,7-Dihydro-Pyrrolo-Pyridine Derivatives PFIZER INC. (US) 2018-01-04 US claimed
WO-2018002760-A1 5,7-DIHYDRO-PYRROLO-PYRIDINE DERIVATIVES FOR TREATING NEUROLOGICAL AND NEURODEGENERATIVE DISEASES PFIZER INC. (US) 2018-01-04 WO claimed
EP-2519522-B1 SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS ARQULE INC (US) 2014-09-24 EP claimed
US-8501770-B2 Substituted imidazopyridinyl-aminopyridine compounds ARQULE, INC. (US) 2013-08-06 US claimed
EP-2519522-A2 SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS ArQule, Inc. (US) 2012-11-07 EP claimed
US-20110172203-A1 Substituted Imidazopyridinyl-Aminopyridine Compounds ARQULE, INC. (US) 2011-07-14 US claimed
WO-2011082270-A2 SUBSTITUTED IMIDAZOPYRIDINYL-AMINOPYRIDINE COMPOUNDS ARQULE. INC. (US) 2011-07-07 WO claimed
WO-1998032813-A1 NONLINEAR OPTICAL FILMS FROM PAIRWISE-DEPOSITED SEMI-IONOMERIC SYNDIOREGIC POLYMERS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1998-07-30 WO claimed